期刊导航

论文摘要

早期舌癌不同颈部处理方式对无病生存率影响的多因素分析

Multivar iate analysis of impact of differ ent neck tr eatment and prognostic factor s affecting disease - free survival in patients with ear ly- staged squamous cell car cinoma of tongue

作者:刘云生 刘少华 杨春惠 吴正华

Author:LIU Yun- sheng1, LIU Shao- hua1, YANG Chun- hui2, WU Zheng- hua1

收稿日期:2007-12-25          年卷(期)页码:2007,25(06):571-

期刊名称:华西口腔医学杂志

Journal Name:West China Journal of Stomatology

关键字:舌鳞状细胞癌,颈淋巴清扫术,Cox比例风险模型,Cox回归,

Key words:squamous cell carcinoma of tongue,neck dissection,Cox proportional hazard model,Cox regression,

基金项目:

中文摘要

目的探讨影响T1/T2N0M0期舌鳞癌患者无病生存率的影响因素,比较不同颈部处理方式对无病生存率的影响。方法回顾性调查97例舌癌患者的住院病历和随访记录,采用Cox比例风险模型对性别、年龄、T分期、原发灶治疗方式、颈部处理方式和肿瘤细胞分化程度共6个可能影响患者无病生存率的因素进行筛选,Kaplan-Meier法对各影响因素进行生存率分析并计算生存率,log- rank法比较各因素不同水平生存分布的差异。重点考察不同颈部处理方式对生存率的影响。结果T分期、原发灶治疗方式、颈部处理方式和细胞分化程度是影响患者无病生存率的主要因素,其P值分别为P

英文摘要

Objective To analyze the prognostic factors affecting the disease- free survival in T1/T2N0M0- staged patients with squamous cell carcinoma of tongue and compare the effectiveness of different neck treatment modalities. Methods 97 consecutive patients with early- staged squamous cell carcinoma of tongue were included in this study. The treatment and following- up records were reviewed retrospectively. Cox proportional hazard model was used to identify the statistically significant prognostic factors in the 6 potential factors. Kaplan-Meier method was used to estimate the disease - free survival and analyze the survival rate among the different levels, and log- rank method for comparison of the different distribution of the survival. A special focus was on the effectiveness of different neck treatment modalities. Results T stage, treatment methods of primary tumor, the modalities of neck treatment and cell differentiation were statistically significant prognostic factors. The value of P and relative ri(sk RR)were P

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