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论文摘要

桂皮醛用作鼠牙牙髓切断术盖髓剂的组织病理学研究

Histopathology r esear ch of Cinnamaldehyde as pulp- cap of pulpotomy in r ats

作者:高洪岩 李文颜 郝太国 刘红英

Author:GAO Hong- yan1, LI Wen- yan1, HAO Tai- guo2, LIU Hong- ying1

收稿日期:2007-10-25          年卷(期)页码:2007,25(05):429-

期刊名称:华西口腔医学杂志

Journal Name:West China Journal of Stomatology

关键字:桂皮醛,鼠,盖髓剂,

Key words:Cinnamaldehyde,rats,pulp- cap,

基金项目:

中文摘要

目的探讨桂皮醛对大鼠根髓及根尖周组织的刺激性,为开发桂皮醛用作乳牙活髓切断术的盖髓剂提供实验依据。方法应用桂皮醛作为鼠牙牙髓切断术的盖髓剂。实验分为桂皮醛组、甲醛甲酚组和空白对照组。每组大鼠分别于4周和12周处死,实验牙牙周矩形颌骨骨块固定脱钙后HE染色切片,观察根髓及根尖周组织的病理学变化。结果术后4周时,3组在牙根内、外吸收和牙根钙化方面差异均无统计学意义;在炎症反应方面,桂皮醛组和甲醛甲酚组差异无统计学意义,但是和空白对照组比较,其差异均有统计学意义(P

英文摘要

Objective To investigate the stimulation of Cinnamaldehyde to the pulp tissue and the periapical tissue of rats′teeth, to provide evidence for developing Cinnamaldehyde as a pulp- cap of pulpotomy in primary teeth. Methods Using Cinnamaldehyde as pulp- cap in pulpotomy of rats′teeth, set up Cinnamaldehyde group, formaldehyde cresol formocresol group and blank group. After different treatment according to the empirical procedure, rats were killed in the 4th week and on the 12th week. Then the experiment teeth and the periodontal tissue were made into HE slides and observed using light microscope. Results The 4th week,internal absorption, external absorption, and calcification were of no significance among all the groups. Inflammation in blank group was far more severe than that in other two groups(P

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