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论文摘要

口腔地米溃疡糊剂中地塞米松质量浓度的测定

Determination of the Content of Dexamethasone Acetate in Stomatology Ulcer Pasta

作者:韩绍兴 杨凡 曾虹

Author:HAN Shao- xing, YANG Fan, ZENG Hong

收稿日期:2007-06-25          年卷(期)页码:2007,25(03):278-

期刊名称:华西口腔医学杂志

Journal Name:West China Journal of Stomatology

关键字:地塞米松,异烟肼比色,质量浓度测定,溃疡糊剂,

Key words:dexamethasone acetate,isonicotinyl hydrazine colorimetry,content assaying,ulcer pasta,

基金项目:

中文摘要

目的为口腔地米溃疡糊剂的质量标准提供质量浓度测定的依据。方法采用异烟肼比色测定口腔地米溃疡糊剂中地塞米松的质量浓度。结果地塞米松的质量浓度为6~16 μg/mL时,吸收度与地塞米松对照品质量浓度线性关系良好。地塞米松平均回收率为98.9%,地塞米松质量浓度相对标准偏差小于1%(n=5)。结论异烟肼比色测定地塞米松质量浓度简便易行、准确可靠。

英文摘要

Objective To provide content- measuring evidences for establishing the quality criteria of dexamethasone acetate ulcer pasta. Methods Content of dexamethasone acetate was assayed by the isonicotinyl hydrazine(INH) colorimetry. Results The good linear range was 6 - 16 μg/mL(r=0.999 1). The average recovery of dexamethasone acetate was 98.9%, and relative standard deviation was low than 1%(n=5). Conclusion It is easy, convenient, accurate and dependable for INH colorimetry to determine the content of dexamethasone acetate.

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