Objective To evaluate the effects of GLUMA desensitizing bonding system in desensitizing hypersensitivity of vital abutment.Methods 69 central incisors with vital pulp from 69 patients were randomly divided into A, B and C group. After tooth preparation, group A coated with primer after etching, group B coated with primer after etching cervical dentin only, and group C was control group without special treatment. The cold sensitivity of abutments was tested after coating with primer, after cementation of crown and three months later. Two fresh extracted caries and restoration-free middle incisorwere prepared in routine way. The surface of specimen 1 was etched with conditioner and the control specimen 2 was prepared without any special surface treatment. Scanning electron microscope(SEM) observation was used to examine the details on dentin surface.Results In all three times of examination, the sensitivities of two experimental groups had been significantly reduced compared with the control group. Immediately after coating, group B were more sensitive than group A (P