Objective The purpose of this study was to investigate the changes of basic fibroblast growth factor (bFGF) ex- pressed in normal human dental pulp at different root development stages of permanent teeth.Methods Based on the teeth root development status, the pulp tissues were classified into three groups: root just starting development, being in development and apical closed. The pulps were immunohistochemically examined by use of bFGF antibody.Results Stainingwas strongly positive in immature permanentteeth, especially atthe stage of root just starting development. Image analysis indicated thatthe gray values of positive reaction in three groups were statistically different (P
