下颌骨可压缩性的动物实验研究
Mandibular Condensability and Length Contraction: An Animal Experimental Study
作者:李 勇1,田卫东2,张志杰1,邓 锋1,钟大文1,王志彬1,戴红卫1,何 玫1
Author:LI Yong1,TIANWei-dong2,ZHANG Zhi-jie1,DENG Feng1,ZHONG Da-wen1,WANG Zhi-bing1,DAI Hong-wei1,HE Mei1
收稿日期:2004-02-25 年卷(期)页码:2004,22(01):16-
期刊名称:华西口腔医学杂志
Journal Name:West China Journal of Stomatology
关键字:下颌骨,可压缩性,动物实验,
Key words:mandible,condensability,animal-study,
基金项目:重庆市卫生局科研课题基金(99-2012)
中文摘要
目的 探讨下颌骨长度的可压缩性。方法 山羊6只,单侧实验,口外进路,下颌角区保留骨松质连续性的颊舌侧骨皮质切开术,采用特制压缩器械,每3 d加力1次,每次压缩0·5 mm。结果 压缩48~78 d后,下颌骨缩短0·8~1·3 cm,下颌骨升支下段前移,下颌角变钝,但因对侧下颌的缩结,咬合变化不大;X线片见压缩区显示骨质密度先是减低,然后逐渐增高,最后完全与正常区一致;HE染色显微镜下可见,在整个压缩和固定阶段,骨切口线一直存在并充满不同成熟程度的成纤维细胞、软骨组织和骨组织。3种结构之间可见组织过度表现。随着固定时间的逐渐延长,纤维组织和软骨组织逐渐变窄,最后骨切口线消失,并为骨组织所完全取代。结论 下颌骨在采用颊舌侧骨皮质切开术并配合外力加压的情况下其长度是可以缩短的,机制为切口两边的骨质先溶解再成骨最后完成改建。
英文摘要
Objective To investigate the condensability of mandibular length.Methods In six goats were used in the study. Corticotomy at right mandibular angleswas performed via extral-oral accession. Special deviceswere applied to shorten the mandi- ble by 0·5 mm per three days respectively.Results ①Mandibular angles of the six goatswere shorten by 0·8 cm to 1·3 cm re- spectively in 48 days to 78 days;②In spite of the lower ascending ramus moving forward and angles being blunt, the occulusion scarcely varied because of contralateral bite-lock;③X-ray demonstrated that, at first, bone density in contracted areas declined , and then increased gradually to almost normal density;④Under microscope there were three tissues layers from central to lateral within the bone gap: fiber layer, cartilage layer and bone layer, and fiber layer gradually transform into cartilage layer with the fixed time. At the end of fixation they all transform into bone tissue.Conclusion Contraction osteogenesis is actually a process of compression, absorption and rebuilding. It is feasible that using contraction osteogenesis to shorten the mandible via cortcotomy.
下一条:大鼠牙囊细胞体外培养技术的建立及其鉴定
【关闭】