超高分子量聚DL-乳酸可吸收骨折内固定系统治疗下颌骨骨折的实验研究
Experimental Research with Animal on Super-high Molecular Weight Poly-DL-lactic Acid Internal Fracture-fixing System Used to Treat Mandible Fracture
作者：郑谦,刘磊,魏世成,赵宗林,熊成东,罗福成
Author：Zheng Qian, Liu Lei, Wei Shicheng, et al
收稿日期：2002-08-25 年卷（期）页码：2002,20(04):283-
期刊名称：华西口腔医学杂志
Journal Name：West China Journal of Stomatology
关键字：超高分子量聚DL-乳酸,下颌骨骨折,骨折内固定,犬,
Key words：poly_DL_lacticacid,mandible fracture,internal fracture_fixing systemdogs,dogs,
基金项目：
本课题为国家863计划资助项目(编号715-002-0141)
中文摘要
目的:观察超高分子量聚DL-乳酸(PDLLA)骨折内固定系统治疗犬下颌骨骨折的疗效及安全性。方法:采用超高分子量PDLLA骨折内固定系统对犬下颌骨骨折进行内固定。在术后1年内,观察其活体状况、大体解剖学形态、下颌骨折区处X线片表现、组织病理学变化。结果:超高分子量PDLLA骨折固定系统用于治疗犬下颌骨骨折具有机械强度高、固定效果可靠等优点,与金属内固定系统的疗效相似。而且PDLLA降解、吸收速度适中,生物相容性良好,既能保证骨折的正常愈合,又避免了金属接骨板的应力遮挡效应。结论:超高分子量聚DL-乳酸是一种理想的骨折内固定系统。
英文摘要
Objective:The purpose of this study was to evaluate the safety and therapy effects of super-high molecular weight poly-DL- lactic acid (PDLLA) internal fracture-fixing system on the treatment of mandible fracture in dogs.Methods:The authors treated dogscmandible fracture with super-high molecularweight polylactic acid internal fracture-fixing system and observed the activity of these dogs. In 1, 3, 6, 12 months after the operation, the authors took the specimens out from dogs and evaluated with anatomi- cal, pathological and radiographic methods.Results:The therapeutic effects of super-high molecularweight PDLLA internal frac- ture-fixing system are similarwith that of stainless steel internal fracture-fixing systems.Conclusion:Super-high molecular weight PDLLA internal fracture-fixing system can be used in the treatment of mandible fracture.
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