Objective To evaluate the effect of Fe2O3 and CeO2 as colorants on yttria stabilized tetragonal zirconia polycrystals (Y-TZP) powder.Methods The spray granulation slurry of colored zirconia was prepared with different concentrations of Fe2O3 (0.15%) and CeO2 (4%), which were added in Y-TZP. Zirconia powder was made by spray granulation. The powder specimens were divided into three groups: uncolored zirconia, Fe2O3 (0.15%) zirconia, and CeO2 (4%) zirconia. The particle morphologies of the powder specimens were measured with a laser particle size analyzer and an optical microscope.Results The differences in D50 among the three groups were statistically significant (P0.05). Mostly spherical powder was observed in the three groups.Conclusion Fe2O3 as a colorant can affect particles, whereas CeO2 has no effect.