期刊导航

论文摘要

妊娠期药物动力学及口腔感染性疾病的安全用药

Pharmacokinetics and drug safety of oral infectious disease during pregnancy

作者:李宏宇, 周雅川, 周学东, 郑黎薇

Author:Hongyu Li, Yachuan Zhou, Xue-dong Zhou, Liwei Zheng

收稿日期:2017-08-13          年卷(期)页码:2018,36(3):319-319-324

期刊名称:华西口腔医学杂志

Journal Name:West China Journal of Stomatology

关键字:妊娠,口腔保健,药物动力学,药物利用,

Key words:pregnancy,oral health,pharmacokinetics,medication,

基金项目:国家自然科学基金(81470711);国家卫生和计划生育委员会儿童口腔国家临床重点专科建设项目(0040305401313)

中文摘要

妊娠期妇女因其所处生理阶段的特殊性,各项生理指标会有所变化,发生口腔疾病的风险急剧增加,对口腔感染性疾病不及时治疗或不合理用药可能会导致胎儿畸形甚至流产。本文对妊娠期药物动力学改变、妊娠期用药原则及治疗口腔感染性疾病常用药物进行综述,为口腔科医生对处于妊娠期口腔感染性疾病患者安全用药提供参考。

英文摘要

Pregnancy is a time of particular vulnerability in terms of physiologic changes resulting in higher risk of oral infectious diseases. There is emerging evidence showing that irrational dental treatment and drug therapy are associated with adverse pregnancy outcomes, including infant malformation or spontaneous abortion. This article reviews the pharmacokinetics of medications in pregnant women and the fetus and introduces a guideline for drug therapy and common dental drugs used during pregnancy.

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