Objective To discuss the effect of music in relieving pain during orthodontic treatment.Methods One hundred and sixty-five cases who wore arches the first time were selected and treated. These patients were randomly divided into two groups:Music group and blank group. The music intervention was used in reducing orthodontic treatment pain, while blank group experienced no intervention measures. Visual analogue scales(VAS) were adopted tor ecord patients’perception of pain, and Eysenck personality questionnaire(EPQ) to evaluate personality traits of all samples.ResultsIn 165 patients, 85.45% were effective. The music group showed significantly less pain than the blank group(PConclusion Music helps to relieve pain during orthodontics treatment. The effect of music to relieve the pain during orthodontics treatment for the males are better than that for the females, extroverted personality ones are superior to introversive personality ones, and the steady-minded patients are better than irritability ones.