ObjectiveTo evaluate the reliability and validity of the Chinese version of the 5-item oral health impact profile (OHIP-5).MethodsAccording to the international guidelines, the Chinese version of the OHIP-5 was produced. It was applied to patients who visit our clinic. The reliability of the scale was evaluated by internal consistency reliability and test-retest reliability. In addition, the validity of the scale was evaluated by construct validity and convergent validity.ResultsA total of 556 patients were enrolled in the study. The Cronbach’s alpha and the intraclass correlation coefficient values (ICC) of the Chinese version of the OHIP-5 were 0.868, 0.831, respectively. The results of the confirmatory factor analysis (CFA) showed that the one-factor model provided an acceptable fit to the data. The fit indices were: the chi-square fit statistics/degree of freedom (χ2/df)=2.419, the goodness-of-fit index (GFI)=0.995, the adjusted goodness of fit index (AGFI)= 0.960, the normed fit index (NFI)=0.996, the incremental fit index (IFI)=0.997, the Tucker-Lewis index (TLI)= 0.985, the comparative fit index (CFI)=0.997, and the root mean square error of approximation (RMSEA)=0.070. For the convergent validity of the scale, the Spearman’s rank correlation coefficient was 0.674.ConclusionThe Chinese version of OHIP-5 had a good reliability and validity by rigorous psychometric properties. Overall, it can be further promoted in clinical research and epidemiological investigations.