A method of power quality real-time status diagnosis based on cloud model was proposed.The normal cloud model for each power quality index was established based on long-term power quality data of each monitoring point.The anomaly threshold determined by the normal cloud outline was used to diagnose the power quality status in the process of monitoring.This method can accurately identify the abnormal power quality status,and find out the potential issue of abnormal operation on the basis of long-term operation characteristics of the power grid. Practical engineering example proved the validity and practicality of the proposed method.