16 square-section concrete columns confined by CFRP sheet were tested in uniaxial compression involved in different preload ratio and CFRP plies. The failure characteristic and mechanics behavior of confined concrete columns were presented, and the descending of the peak stress and strain of confined concrete due to preload were analyzed. The experimental results indicated that the confinement effect of CFRP was influenced by preload ratio observably. The second stiffness, the peak stress and strain declined with preload ratio ascending, and the extent developed with the enhancement of CFRP ply.