In order to predict bank failure in MLYZ after the operation of Three Gorges Project (TGP), Stable Slope (SS) was introduced to distinguish whether bank collapsed based on the analysis of characteristics of bank failure. SS of different river type and geological conditions of bank was analyzed, and the calculation formulas of erosion depth of thalweg were also explored. Based on that, the Actual Slope (AS) was calculated and compared with SS, the location where bank collapsed was forecasted. Comparative analysis between prediction result and observed data of Jingjiang Reach after the operation of TGPI ndicated that the method is reasonable and applicable.