In order to supply the downlink receiver design of practical LTE system with effective prior information, downlink 4×2 high order MIMO antennas configuration was considered. Firstly, the received signal model of downlink hybrid MIMO transmission schemes was presented in LTE systems, and then Minimum Mean Square Error(MMSE) equalizer and Maximal Ratio Combination(MRC) equalizer were designed to suppress the hybrid interferences, respectively. Furthermore, for improving system simulation efficiency, a modified formula of Signal to Interference plus Noise Ratio(SINR) based on modifying factor was deduced from the random perturbation assumption of channel response matrix. Finally, the hybrid MIMO transmission schemes were considered in downlink LTE system simulations, and throughput curves of target user with different scheme were drawn. The results showed that MMSE equalizer performs better than MRC equalizer, and has important reference value for analyzing actual LTE system performance.