After extracted from Voacanga africana Staph., the crude sample was purified and recrystallized to get polycrystalline powder. The crystal structure of Hydrochloride Tabersonine was determined from its X-ray powder diffraction pattern through calculational crystallography methods.The results showed that the the caystal structure of hydrochloride tabersonine is monoclinic,space group P21 with unit cell dimensions a=1.253 9 nm，b=0.737 1 nm，c=1.229 6 nm，α=γ＝90°，β＝106.192°，Z=2，V=113.649 7 nm3.
