氟氯苯菊酸的合成工艺优化
Optimization of the synthetic process of fluoropermethrin
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收稿日期： 年卷（期）页码：2020,35(03):-237-239
期刊名称：华西药学杂志
Journal Name：WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字：氟氯苯菊酸;合成工艺;优化;对氯苯乙酮;固体三光气;正交实验;单因素试验;工业化生产
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中文摘要
目的优化氟氯苯菊酸的合成工艺。方法改用廉价的对氯苯乙酮及稳定的固体三光气为原料,合成氟氯苯菊酸;同时采用正交试验、单因素试验对反应条件进行优化。结果经4步反应,成功制得了氟氯苯菊酸,提高了产物的收率。结论所用方法可满足工业化生产的要求。
英文摘要
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