Objective To observe the expression of angiopoietins in oral squamous cell carcinoma and relationship between the expression of angiopoietins and pathologic classification.Methods The expression ofAng-1 and Ang-2 protein in samples from42 oral squamous cell carcinoma and 16 oral normal mucosa were detected by immunohistochemical technique.Results The expres- sion of Ang-1 and Ang-2 was found in both oral squamous cell carcinoma and normal control. Itwas found Ang-1 expression alike in oral squamous cell carcinoma and control (P>0.05). Ang-2 expressed at low level in control while strongly positive in oral squamous cell caroinoma and the level of Ang-2 expression in oral squamous cell caroinoma was related to pathologic classification (P
